A well-known cell-survival pathway involves a kinase called _______ that is activated by the _______, leading to a larger chance that the cell will survive a stimulus that would normally lead to its destruction

Answers

Answer 1

Answer:

Protein kinase B (PKB); 3,4,5-triphosphorylated phosphoinositide (PIP3)  

Explanation:

Protein kinase B (PKB) is a kinase protein involved in receptor tyrosine kinase regulatory pathways. This enzyme attaches ATP-phosphate groups to serine/threonine residues in order to alter the activity of target protein substrates. PKB is involved in many cellular processes including transcription, cell proliferation and apoptosis. PKB is activated by the 3,4,5-triphosphorylated phosphoinositide (PIP3) enzyme and then this kinase propagates the signal to Akt (another serine/threonine kinase) by phosphorylation of its catalytic domain. The Akt/PKB signaling pathway is well-known to promote cell survival in response to extracellular signals/stimuli.


Related Questions

Is there a scientific discovery in today’s world that has been overshadowed by popular belief? Explain. What role do you think popular belief has on scientific discoveries?

Answers

The history of science is also a history of people resisting new discoveries that conflict with conventional wisdom.

When Galileo promoted Copernicus’ theory that the Earth revolves around the sun – counter to church doctrine about the Earth being the center of the universe – he wound up condemned by the Roman Inquisition in 1633. Charles Darwin’s theory of evolution – that new species develop as a result of natural selection on inherited traits – ran into opposition because it contradicted long-held scientific, political and religious beliefs. Alfred Wegener’s 1912 proposal that Earth’s continents move relative to each other – the theory of continental drift – was rejected for decades, in part because scientists held fast to the traditional theories they’d spent careers developing.

These kinds of examples aren’t only historical, unfortunately. We’re used to hearing about how the general public can be dense about science. You might expect some portion of everyday folks to take their time coming around on truly groundbreaking ideas that run counter to what they’ve always thought.

But scientists, too, hold their own personal beliefs – by definition, based on old ways of thinking – that may be holding back the innovation that’s at the heart of science. And that’s a problem. It’s one thing for an average Joe to resist evolving scientific theories. It’s quite another if a scientist’s preconceived notions holds us back from discovering the new and unknown – whether that’s a cure for Zika or a cutting-edge technology to combat climate change.

Personal beliefs as publication roadblocks

Real scientific progress occurs when laboratory or field research is reported to the public. With luck, the finding is accepted and put into practice, cures are developed, social policies are instituted, educational practices are improved and so on.

This usually occurs though publication of the research in scientific journals. There’s an important step between the lab and publication that laypeople may not know about – the evaluation of the research by other scientists. These other scientists are peers of the researcher, typically working in a closely related area. This middle step is commonly referred to as peer review.

In a perfect world, peer review is supposed to determine if the study is solid, based on the quality of the research. It’s meant to be an unbiased evaluation of whether the findings should be reported via journal publication. This important step prevents sloppy research from reaching the public.

However, in the real world, scientists are human beings and are often biased. They let their own beliefs influence their peer reviews. For example, numerous reports indicate that scientists rate research more favorably if the findings agree with their prior beliefs. Worst of all, these prior beliefs often have nothing to do with science but are simply the scientists’ personal views.

‘But that’s counter to what I thought…’

How is this a problem for scientific innovation? Let’s look at how some personal beliefs could prevent innovative science from reaching the public.

Minorities aren’t good at STEM.” The stereotype that “women are not good at math” is commonly held – and also happens to be incorrect. If a scientist holds this personal belief, then he is likely to judge any research done by women in STEM (Science, Technology, Engineering and Mathematics) more negatively – not because of its quality, but because of his own personal belief.

For instance, some studies have shown that female STEM applicants in academia are judged more harshly than their male counterparts. Because of this gender bias, it may take a female STEM researcher more time and effort before her work reaches the public.

Some racial minorities face similar kinds of bias. For example, one study found that black applicants are less likely to receive research funding from the U.S. National Institutes of Health than equivalently qualified whites. That’s a major roadblock to these researchers advancing their work.

However, people often believe that comic books are just low-brow entertainment for kids. If a scientist holds this personal belief, then she’s likely to judge any psychology research using comic books more negatively. Because of this, scientists like me who focus on comic books may not be able to publish in the most popular psychology journals. As a result, fewer people will ever see this research.

The history of psychology supplies one example. Behaviorism was psychology’s dominant school of thought for the first part of the 20th century, relying on observed behavior to provide insights. Its devotees rejected new techniques for studying psychology. During behaviorism’s reign, any talk of internal processes of the mind was considered taboo. One of the pioneers of the subsequent cognitive revolution, George A. Miller, said “using ‘cognitive’ was an act of defiance.” Luckily for us, he was defiant and published one of the most highly cited papers in psychology.

The scientific endeavor requires belief. There would be no science if people didn't have faith in the objectivity of other scientists' work.

What is the importance of scientific discoveries?

New techniques, new galaxies, new planets, and potentially even the existence of life on them are just a few of the previously unthinkable possibilities that science has made feasible. Further possibility lies in the future.

Scientism is a very odd word, but for reasons we will see, it is an important one. Despite being a relatively new term, it is connected to numerous other “isms” that have a long and violent history.

The moral standing of professors and mentors, the order and understanding of nature, and the compatibility of reason and truth.

Therefore, scientific discovery in today’s world that has been overshadowed by popular belief.

Learn more about scientific discovery here:

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PLZ HELP GIVEING BRAINLIST

6. All organisms must obtain energy from their environment. Every organism needs this energy in order to grow and reproduce. How do producers obtain energy?

They obtain energy by eating plants, bacteria, and algae
They extract chemical energy from decaying organic matter
They extract energy from the chemicals in soil, air, and water.
They capture energy from sunlight and manufacture their own food

Answers

they capture energy from sunlight and manufacture their own food

Please answer this thank you

Answers

Answer:

I thinks its B

Explanation:

Photosynthesis and respiration depend on each other for the exchange of:

Answers

Carbon dioxide and Oxygen
carbon dioxide and oxygen hope it helped!

Which product of respiration is used for tissue repair and cellular function?

carbon dioxide
water
energy
oxygen

Answers

Answer:

energy c

Explanation:

Its

Answer:

energy

Explanation:

This substitution score matrix called _____ is derived from protein families that are characterized by blocks of conserved amino acid sequences.

Answers

Answer:

BLOSUM

Explanation:

A substitution matrix is a matrix used in bioinformatics (and also in computational biology) to determine/estimate the rate at which one character -which is specified by a nucleotide sequence in nucleic acid alignments or by one amino acid in protein alignments-, changed to another character during the course of the evolution. The BLOcks SUbstitution Matrix (popularly known as BLOSUM) is a substitution matrix used to score one amino acid for another in a protein alignment. The BLOSUM substitution matrix is particularly useful to compare evolutionarily conserved regions between protein sequences and thus score their alignments, where each entry is indicated by a similarity score between two amino acids.

The negative effects of
include flash floods, mudslides, and droughts.

Answers

Answer:

Deforestation would be your answer.

hope it helps!

A two-substrate enzymatic reaction in which one product is produced before the second substrate binds to the enzyme has a

Answers

Answer:

The correct answer is - Ping pong Mechanism.

Explanation:

The ping pong mechanism of the enzyme is a non-sequential mechanism of two-substrate enzymatic reaction in which product is produced after the binding with the first substrate.

After the produced form due to the binding of the enzyme to the first substrate, it changes into a temporary form that binds with the second substrate and completes the reaction.

Thus, The correct answer is - Ping pong Mechanism.

Observe an ecosystem near your home and describe the biodiversity of your chosen ecosystem. PLZZZ HELPP idc if its from a photo just Helpp mee

Answers

Answer:

A garden is a ecosystem that is near my house.  the biodiversity of garden is fresh green leaves for caterpillars, and floral resources (pollen and nectar) for pollinators.

Explanation:

Hope it helps!!!!!

Mark me brainlist plzzzzzzzzzzzzzzzzzzzzzzzzz

An object with a mass of 30 kg is located on a cliff 50 m above the ground. What is its gravitational potential energy

a. 1500 j
b. 14,700 j
c. 1.7 j​

Answers

b. 14,700 J

Because,

Potential energy

= m.g.h

= 30 kg × 9.8m.s^-1 × 50m

= 14700 kg.m^2.s^-2

= 14700 J

a country with different habitat is described as high degree of?..​

Answers

Answer:

Habitat diversity.

Explanation:

Biodiversity means the diversity of living organisms that make up land and water, as well as the diversity within different species, between species and ecosystems. Biodiversity is not only the overall diversity of forms and phenomena of flora and fauna but also the diversity of the function of living organisms.

Chromatography is an analytical test used to closely examine which aspect of fibers? *
1 point
Cross Section
Light Absorbtion
Dye Composition
Fiber Composition

Answers

Dye composition

Hope it helped you

Which is the most efficient way to avoid DNA mutations from UV radiation?

Answers

Answer:

Hi, I belive the correct answer your looking for is C. Avoid Uv radiation by wearing sunscreen.

Explanation:

Why?- Well the first two A,B are incorrect because X-rays cant really protect you from Uv radiation and The last one D a tanning bed are you kidding me nope definitely wrong.

Answer:

c

Explanation:

Help please I'll give brainlist
The environment limits population growth by changing birth and death rates. Briefly describe how each environmental factor listed below influences population size. Also, identify each environmental factor as a biotic or abiotic factor

Competitors
Disease
Food
Ph level
Prediction
Soil type
Temperature
Water availability

Answers

Answer:

Disease

Ph level

Water availability

Soil type

Explanation:

A fungus with white spores cross fertilizes a fungus with black spores. If 10% of the progeny bear white spores while 90% of the progeny bear black spores, what must be true?
A.
The trait for spore color is determined by exactly one gene.

B.
The trait for spore color is determined by more than one gene.

C.
The allele for black spores is dominant over that for white spores.

D.
The allele for white spores is dominant over that for black spores.

Answers

Answer:

C.

Explanation:

Since there are more of an outcome of black spores it would make sense that this trait is dominant.

White spores seem to be recessive in this case too.

I also suspect the parents are both heterozygous. They both carry one trait for black and one for white.

Hopefully this is correct. Have a great day.

Answer:

B. The trait for spore color is determined by more than one gene.

Explanation:

Took the test.

PLZZZ HELP ME Which of the following is NOT a characteristic of plants?
O Create food through photosynthesis
O Multicellular organisms
O Incapable of movement
O Capable of moving by themselves

Answers

uh i would say the last option ?

What does this process lead to?
Chiasma

Answers

Answer: Chiasmata are specialized chromatin structures that link homologous chromosomes together until anaphase I (Figs. 45.1 and 45.10). They form at sites where programmed DNA breaks generated by Spo11 undergo the full recombination pathway to generate crossovers. At a given chiasma, an exchange of genetic material can occur between both chromatids, what is called a chromosomal crossover, but this is much more frequent during meiosis than mitosis. In meiosis, absence of a chiasma generally results in improper chromosomal segregation and aneuploidy.

Hope this helps........ Stay safe and have a Merry Christmas!!!!!!!! :D

Which part of the leaf most likely produces the most glucose

•the green part, because it contains the chlorophyll

•the white part, because it contains the chlorophyll

•the green part, because it contains carbon dioxide

•the white part, because it contains carbon dioxide

Answers

Answer:

green part that contains chlorophyll

Answer:

A. the green part, because it contains the chlorphyll

Explanation:

What is one way the body lowers its temperature?

Answers

Answer:

Sweating

Explanation:

Sweating is your body's way of naturally reducing body temperature. By sweating, your body releases heat then the sweat on your body cools down, eventually, cooling your body down.

Answer:

if your talking about heat, then the body starts sweating to cool its self down.

Explanation:

Peristaltic action ensures food is pushed through the

Answers

Answer:

Peristaltic action ensures food is pushed through the Esophagus.

hope it helps!

Which of the following are outputs of photosynthesis that are used as inputs for cellular respiration? [SELECT ALL THAT APPLY]

a. H20
b. CO2
c. O2
d. C6H12O6

Answers

A.H20 because I have to know

) What happens when a phosphate group is removed from an ATP molecule?
a. carbohydrates are stored b. water is released
c. energy is stored
d. energy is released

Answers

Answer:

D. energy is released

Explanation:

In the process of hydrolysis, a phosphate group is removed and energy is released. This then converts the ATP molecule into ADP (adenosine diphosphate).

Movement of individuals into or out of the population, called gene flow, impacts evolution of populations because:_________.
a. it can lead to extinction of one or more populations.
b. it may cause genetic drift.
c. it leads to a redistribution of alleles
d. adaptive radiation results.
e. a founder effect will occur.

Answers

Answer:

c. it leads to a redistribution of alleles

Explanation:

The gene flow can be defined as the movement of genetic material from one population to another within the same species. This movement may be associated 1-with the migration of individuals and subsequent reproduction of these organisms in the new population or 2-with the movement of gametes (eg., pollen dispersal) among populations. In both cases, gene flow is known to alter the frequency of particular alleles between populations and consequently also modify the evolutionary patterns of these populations.

Gene flow is the migration of genes or alleles and refers to the transfer of the genetic material. If the rate of the gene flow is high then two populations will say to be an effective population.

It just leads to redistribution of the genes or alleles with the in the popualtion  of species. Hence the option C is correct.

Learn  more about the individuals into or out of the population, called gene flow.

brainly.com/question/12021027.

The nitrogen cycle describes how nitrogen is converted between different forms. Describe the nitrogen cycle process by completing the sentences.
1.Atmospheric Nitrogen (N_2) is converted to NH3 in a process catalyzed by __________.
2. NH_4+ is _________ to NO_2- and then NO_3- in a process called ___________.
Atmospheric nitrogen is __________ to NH_4+ as a result of ____________.
Nitrate is converted to N_2 in a process called ______________.
Nitrite conversion to NH_4+ is catalyzed by ______________.

Answers

Answer:

1. Nitrogenase

2. converted, nitrification

3. Decayed, ammonification

4. Denitrification

5. nitrite reductase

Explanation:

The nitrogen cycle refers to the series of processes that adds and removes nitrogen from the soil or atmosphere. The series of processes involved in nitrogen cycle are being described in this question as follows:

- Atmospheric Nitrogen (N2) is converted to NH3 (ammonia) in a process catalyzed by the enzyme NITROGENASE in a process called nitrogen-fixation.

- NH4+ (ammonium ion) is converted to NO2- (nitrite) and then NO3- (nitrate) in a process called NITRIFICATION.

- Atmospheric nitrogen (N2) is decomposed or broken down to NH4+ (ammonium ions) as a result of a process called AMMONIFICATION.

- Nitrate is converted to atmospheric nitrogen (N2) in a process called DENITRIFICATION.

- Nitrite conversion to ammonium ion (NH4+) is catalyzed by an enzyme called NITRITE REDUCTASE

fill in the blanks human beings continue to grow Till the age of dash​

Answers

Answer:

Human beings continue to grow till the age of 20.

Answer:

most people don't reach full maturity until the age of 25

Match the type of water with the location in which it is found. surface water ,water vapor, atmosphere, well ,glacier ,river, groundwater ,ice. ​

Answers

Answer:

Surface water <---> river

Ground water <------> well

Water vapour <------> atmosphere

Glacier <-------> ice

Explanation:

Answer:

Plato

Explanation:

PLEASE HELP ME ILL MARK BRAINLIEST CORRECT ANSWer thank you

Answers

Answer:

I think it might be C. .......

Explanation:

Osmosis which is a form of passive transport

Answers

Answer:

represents the flow of water through its concentration gradient, through a semi-permeable membrane.

Explanation:

This means that water flows from where it is in a higher concentration to a place where it is in a lower concentration to try to equalize the concentrations of both solutions.

Osmosis is an example of diffusion when molecules tend to be evenly distributed in space.

The Sun is a fairly normal star.
True
False

Answers

Answer:

Yes.

Explanation:

The Sun is a medium sized star

What could a weather forecast on Mars be?

Answers

Temperatures on Mars are in the extreme negatives besides on the poles. So very cold and dry. But the poles can get to +70 degrees, so they can be warmer

Answer:

Cold

Explanation

Weather conditions on Mars

Mars is an extremely cold planet with an average temperature around minus-80 degrees. Temperatures can dip to minus-225 degrees around the poles. Periods of warmth are brief — highs can reach 70 degrees for a brief time around Noon at the equator in the summer.

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