Answers
Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
Normal hemoglobin protein in a RBC
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
Sickle cell hemoglobin protein in a RBC
DNA CTG ACT CCT GTG GAG AAG TCT
Amino acids Leu Thr Pro Val Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease.
Related Questions
what are the two reservoirs for nitrogen
Answers
Answer: Atmosphere and Continental Crust
Upwelling or Biodiversity
Answers
why do all minerals look different
Answers
Answer:
All minerals are inorganic, they have a crystal structure, their solids, and they are naturally formed. Minerals are classified in 7 different ways. Their color, luster, streak, cleavage and fracture hardness, density, and special properties identify them. ... Tanzanite is found only in metamorphic rock.Explanation:
please follow meeHeartworms are parasitic what?
O Hookworms
O Roundworms
O Tapeworms
O Earthworms
Answers
Answer:
tape worms i think
Answer:
D. Roundworms I believe sorry if wrong ;)
Explain how baking soda and vinegar is a chemical reaction
Answers
Answer:
Explanation:
Baking soda and vinegar react chemically because one is a base and the other is an acid. ... The first reaction is the acid-base reaction. When vinegar and baking soda are first mixed together, hydrogen ions in the vinegar react with the sodium and bicarbonate ions in the baking soda.
How can an increase in the falcon population cause an increase in plant population ?
Answers
Explanation:
the eat what eats the plants
Answer:
Hawks might eat herbivore animals, meaning less plants will be eaten by them as there are less
Reflecting telescopes use mirrors as well as lenses.
Please select the best answer from the choices provided
T
F
Answers
Answer: true
Explanation:
Can someone help asapp
Answers
Answer:
option A
hope it helps! please mark me brainliest
thank you! have a good day ahead
if u follow me, I will follow u back
The life span of a star depends on:
plz hurry :)
Answers
Answer:
It's size
Explanation:
Answer:
mass
Explanation:
The lifetime of a star depends on its mass. Since stars spend about 90% of their lives burning hydrogen into helium on the main sequence, their main sequence lifetime is also determined by its mass.
what will happened if two people with equal mass standing on skateboads pushed against each other
Answers
It is possible for some species in a food we’d to be a primary consumers and a secondary consumer at the same time?
1- true
2- false
Answers
explanation:
Are there organisms that can be abiotic and biotic?
Answers
Examples of abiotic factors are water, air, soil, sunlight, and minerals.Biotic factors are living or once-living organisms in the ecosystem.
Biotic describes a living component of an ecosystem; for example organisms, such as plants and animals.
Examples Water, light, wind, soil, humidity, minerals, gases.
Hope this helps!
What is a network of water-filled canals with thousands of tube feet called?
Answers
Plant and Animal Cells
What is the name of this organelle?
Answers
Answer:
Golgi apparatus
Explanation:
Suppose you are on a class field trip to collect fossil shark teeth in the Sandy Beach. Which of the following tools would be best for your teacher to take long for you to use to collect the shark's teeth? Choose all that apply.
A. Mobile x-ray machine (uses x-rays to "see" inside things)
B. Hand trowel (a small shovel with a pointed tip)
C. Hand sieve (separates particles of different sizes)
D. Power drill (hand-held tool that drills holes in things)
Answers
Answer:
B
Explanation:
does facilitated diffusion require an input of energy?
Answers
Answer:
No
Explanation:
Facilitated Diffusion is a type of passive transport. Passive transport does not require energy to happen. Passive transport includes Diffusion, Facilitated Diffusion, and the intake of water molecules.
Which of the following is NOT associated with a
loss of biodiversity?
A. more healthy and stable ecosystems
B. extinctions
C. loss of natural resources
D. loss of potential foods & medicines
Answers
The two diagrams below represent a sugar molecule and a fat molecule 1 point that is used by living organisms. Which statement best describes these two molecules?
What is a bacteria that is beneficial to humans and what does it do?
Answers
How will you react if I tell you that your body consists of 1 to 2.6 kg of bacteria? Shocked? Well, I can imagine your surprised face. Most people believe that bacteria are dangerous and are responsible for diseases and infections but this isn’t true. In fact the truth is, most of the bacteria are helpful in the functioning of a living body and are also capable of performing many other useful functions. These beneficial bacteria are present in huge numbers inside as well as outside our body. Well let’s check out various types of beneficial bacteria which not only help in proper functioning of our body but also contribute in many other functions in and outside the body. Some of the examples of helpful bacteria are Bifidobacterium, Rhizobium and E.coli.
Beneficial Bacteria – to Humans
Human body has millions of bacteria which participate in different functions of the body. As you know the amount of bacteria present in the body varies from 1 to 2.6 kg, this volume contains a huge number of bacteria. These bacteria can be present in all parts of the body but mostly they are found in the intestine where they help in the process of digestion. They also play a very important role in preventing bacterial infections in genital parts, like yeast infections. Some beneficial bacteria to humans are helpful in maintaining the pH of the body. Some are even involved in protecting the skin from many infections.
They are also helpful in the production of vitamin K and have an important role to play in the functioning of immune system. One of the most common bacteria which are helpful for humans is Escherichia coli. This bacteria is associated with the process of digestion. It is present in the large intestine where the maximum digestion takes place. These bacteria release enzymes which help in the process of digestion and synthesis of various vitamins and nutrients. Beneficial bacteria are also very helpful for the pregnant women. They reduce the chances of postpartum complications and also protects the baby from fungal infections.
Answer:
Probiotics are live bacteria that are good for us, that balance our good and bad intestinal bacteria, and that aid in digestion of food and help with digestive problems, such as diarrhea and bellyache. Bacteria that are examples of probiotics are Lactobacilli and Bifidobacterium.
Visit a grocery store and look at the packets and cans of different food items.Read the details given on them ,find and note the energy they contain.Make a list of various food items(at least ten)and the amount of energy they contain in kilojoules per 100gm or 100ml.Also mention whic food contain most energy and which contain least energy.
Answers
Answer:
Sweet Corn - 395KJ
Fruit cocktail - 265KJ
Marshmallow - 342KJ
Tuna fish - 132 KJ
beans - 600KJ
noodles - 1600KJ
chips - 458KJ
Soup - 140KJ
cookies - 1761KJ
Juices - 350KJ
Explanation:
The canned food are packed with special packaging material to make the food item freshness last longer. The food items are preserved in tin packs with airtight packaging.
Please help!!
When purchasing an electrical device, what are the two financial costs you need to consider? Are there any environmental considerations you would make? Explain your reasoning.
Answers
Answer:
Initial price and operating cost
Identify the triangle that contains an acute angle for which the sine and cosine ratios are equal.
B А
B
A
40°
450
22
60°
45°
30
50
B
B
68
A
А
Answers
50 i think
Explanation:
be cause a right angle is 90 so if the acute angle is smaller it should be a smaller number but its hard to say without an image to help us out
Please help It is making me cry
Answers
Answer:
What are you supossed to be doing
Explanation:
Answer:
Can you give me the answers?
Explanation:
The verb concentrate means "gather" or "collect." The suffix -ion, used to form nouns, means "state" or "condition." Use this information to define the noun concentration.
Answers
Answer:
The state of gathering together.
Explanation:
Concentration is a noun and it refer to the act of gatthering closely or the state of gathering together or condition of collecting things or substances together.
In biochemistry it can mean the measure of the ratio of mass to volume in a solute and ratio of mass to volume of a solvent in a solution.
If I wanted to prepare to run a marathon, what type of macromolecule would I want
to consume?
Answers
Answer:
Complex Carbohydrates
Explanation:
There are different types of macromolecules and they all have different purposes, but for a marathon carbs, specifically, complex ones would be best. This is because carbs are the main source of energy for the body. Additionally, unlike proteins, they allow for long-term energy; so you could run an entire marathon without running out of energy.
How is energy related to the change of state
represented by the model?
O Atoms gain energy as a gas changes to a solid.
O Atoms gain energy as a gas changes to a liquid.
O Atoms lose energy as a gas changes to a solid.
O Atoms lose energy as a gas changes to a liquid.
Answers
Answer:
Atoms lose energy as a gas changes to a solid. How is energy related to the change of state represented by the model? Atoms gain energy as a solid changes to a liquid.
Explanation:
Suggest one advantage and one disadvantage of
using a dichotomous key to identify something.
Answers
In multicellular organisms, life begins as a single cell until blank occurs, causing growth
Answers
In the example about the beaver's teeth, is it possible for just one beaver to evolve and get a favorable trait in its lifetime.
A. Yes because it makes sense it would need better teeth to cut down the tree
B. No because all traits are inherited and better teeth would have to come from those beavers with a trait for better teeth
C. Yes because animals control their traits.
Answers
When humans dig-up fossil fuels and burn them to power the modern world, carbon flows between which two reservoirs of the carbon cycle? * A. Hydrosphere and biosphere B. Geosphere/lithosphere and atmosphere C. Atmosphere and biosphere D. Hydrosphere and geosphere/lithosphere
Answers
Answer:
B
Explanation:
When humans dig-up fossil fuels and burn them to power the modern world, carbon flows between the Geosphere/lithosphere and the atmosphere.
Both the geosphere and the atmosphere represent important reservoirs of carbon. The digging-up of fossil fuels, otherwise known as exploration, is carried out in the geosphere or the lithosphere part of the earth. For example, crude oil is obtained deep from the ground. When the fuels are burned, they release carbon in the form of carbon dioxide into the atmosphere.
Hence, it can be concluded that carbon flows from the geosphere/lithosphere part of the earth to the atmospheric portion of the earth when fossil fuels are burned.
The correct option is B.
3. Which of the following is an organelle?
(2 Points)
Mitochodria
DNA
Phospholipid
Nucleus
Answers
Answer:
mitochondria and nucleus