Three human disorders−−fragile X syndrome, myotonic dystrophy, and Huntington's disease−−are conceptually linked by a common mode of molecular upset. Choose the phenomenon that links these disorders. Three human disordersfragile X syndrome, myotonic dystrophy, and Huntington's diseaseare conceptually linked by a common mode of molecular upset. Choose the phenomenon that links these disorders. All three are caused by disparate genes, but each gene was found to contain repeats of the same trinucleotide sequence. All three are X-linked, but each gene was found to contain repeats of the same trinucleotide sequence. All three are caused by disparate genes, but each gene was found to contain repeats of a unique trinucleotide sequence. All three are X-linked, but each gene was found to contain repeats of a unique trinucleotide sequence.

Answers

Answer 1

Answer:

The correct answer is ''All three are caused by disparate genes, but each gene was found to contain repeats of a unique trinucleotide sequence.''

Explanation:

Four groups of trinucleotide repeats related to DNA expansion have been characterized in the human genome. CGGI GCC, CAGIGTC, CTGIGAC and recently GW CTT sequences. The CGGl GCC sequences are usually located in the noncoding regions of different genes and when expanded they associate with fragile sites on the chromosomes. The CAGIGTC repeats are part of the coding region and are related to different neurodegenerative disorders. You can try to make a classification depending on the unit that is repeated, having on one side a group that are caused by repeats of the CAG trinucleotide (cytosine, adenine, guanine). Huntington's disease (HD) is a progressive disorder of motor, cognitive and psychic function. The disease is inherited in an autosomal dominant manner, and is caused by the expansion of CAG trinucleotide repeats in exon 1 of the gene called huntingtin (HTT or IT-15). Unstable mutations have also been found in which the repeat unit does not is composed of three nucleotides, if not four, such as type 2 myotonic dystrophy, where the tetranucleotide CCTG repeats. Fragile X Syndrome consists of an abnormal expansion of the cytosine-guanine-guanine trinucleotide (CGG) in the FMR1 gene, which prevents intellectual disability and also influences the formation of connective tissue


Related Questions

As a runner begins to run a race, his or her respiration rate will increase. The runner begins to breathe deeper and at a rapid rate. In addition, the heart beats more quickly. This will result in more oxygen and nutrients delivered to the muscle cells. Which three body systems are working together to help out the muscle cells?

Answers

Answer:

respiratory system

circulatory system

digestive system

In Respiration, to where is the energy from sugar molecules transferred?

Answers

Explanation:

During the process of glycolysis in cellular respiration, glucose is oxidized to carbon dioxide and water. Energy released during the reaction is captured by the energy-carrying molecule ATP (adenosine triphosphate).

Answer:

its transferred to ATP

Explanation:

during respiration glucose and oxygen is converted into carbon dioxide and water, so the energy is transferrred to ATP

Is it true that a lizard is the venomest creature?​

Answers

Explanation:

While most snakes and lizards in North America are not poisonous, a few species can seriously injure or kill someone with their venom if the bite isn't treated quickly. They include the rattlesnake, copperhead, cottonmouth, coral snake, Gila monster, and Mexican bearded lizard.

Answer:

Yes and No

Explanation:

There are many lizards that are quite harmless to people ( in fact most of them) but you can still find ones that are unusually  furious and deadly , hope this helped :)

At what age does a person begin to think about education and career goals over
relationship with friends?
Ten
Fourteen
Eighteen
Late twenties

Answers

Answer:

Somewhere in the Fourteen-ish and Eighteen-ish, that's just my opinion of this matter.

Eighteen is the perfect age does a person to begin to think about education and career goals over relationships with friends.

What does adulthood teach us?

Being an adult means being responsible for yourself. So instead of doing everything you want to do, you start to compromise. You learned that you need to take care of your problems instead of running away from them. Instead of pulling out an all-nighter, you learn to manage your time better.

After the eighteenth of a person, a person should be considered an adult. Adulthood is a stage where a person considers themselves more responsible for their lives and carrier goals.

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describe properties of minerals.

Answers

physical properties: hardness, luster, color, streak, specific gravity, cleavage, fracture, and tenacity.

Having trouble with this textbook question. Can anyone help me out?
"You learned that the length of the cell cycle varies between cell types. Predict which of the three phases of the cell cycle varies"

Answers

Answer:

Oh well Thx that could really help

Which phrase describes the relative age of a rock?
O uses the law of superposition to determine which rock is older or younger
can determine the age based on location of a rock within the same layer
requires only one rock to determine the age
can provide the exact age of a rock

Answers

Answer:

Hi, there your answer is uses the law of superposition to determine which rock is older or younger.

Explanation:

if you know that a rock was deposited after the one you are attempting age then you know that the "deeper" one is older.

Hope this helps :)

I need help please help

Answers

Answer:

As during the civil war, African elephants with tusks were targeted, and the tuskless elephants were left alone. This, in turn, allowed for the tuskless elephant populace to thrive and continuously grow, while the tusked elephants saw a decline as more and more were poached. So, it is only natural that as time progresses, and assuming the circumstances remain constant, that the tusked elephant population will see a negative trend, and inversely the tuskless elephant population will see a positive trend.

HELP!!! PLZ 10 minutes!!

In aerobic cell respiration, glucose is converted to:
a) H20
b) O2
c) Electrons
d) CO2

Answers

D i believe hopefully it helped

All organisms need energy and
to live, grow, and reproduce. Both of these things cycle
through an ecosystem through its organisms.
sunlight
decomposers
matter
reproduction

Answers

Answer:

Sunlight

Explanation:

state one adaptation of nephron in the kidney of a desert mammal​

Answers

Answer: The desert animals do not get appreciable amount of water quantity to survive on daily basis instead their body mechanism tries to conserve water by concentrating urine.

Explanation:

The desert mammal like kangaroo rat produces hyper concentrated urine so as to conserve water. It is facilitated by extremely long loop of Henle in their nephron. The long loop of Henle increases the time and space for absorption of water and nutrients from the urine filtrate. Hence, urine so produced is more concentrate and conserve water. Moreover, the kangaroo rat consume their urine to survive in extreme hot desert condition in scarcity of water.

Human body systems are made up of organs that work together to perform specie
functions. The circulatory system and the respiratory system have one organ in
common. Which organ is common to both systems?
(A)arteries (B)large intestines (C)stomach (D)heart

Answers

Blood moves in and out of the lungs through the pulmonary arteries and veins that connect to the heart.

Why are terrestrial planets closest to the Sun?

Answers

Answer:

The Sun sent out energy and particles in a steady stream, called stellar winds. These winds proved so strong that they blew off mostthe gases of the four planets closest to the Sun, leaving them smaller, with only their rocks and metals intact. That's why they are called rocky, or terrestrial, planets.

The terrestrial planets formed close to the Sun where temperatures were well suited for rock and metal to condense. The jovian planets formed outside what is called the frost line, where temperatures were low enough for ice condensation.

2-What is the difference between how you grow up and how a caterpillar grows up?​

Answers

as a caterpillar, it will slowly begin the process of turning into a butterfly and at some point, it will go into a cocoon while when humans grow up they slowly grow taller and begin to look different from when they were younger.

Hope this helps - Six

Identify and describe three mechanisms of movement of lymph through the lymphatic vessels.

Answers

Answer: Lymph fluid can only flow forward through lymphangions due to the closing of valves after fluid is pushed through by fluid accumulation, smooth muscle contraction, or skeletal muscle contraction if that makes sense. Without valves, the lymphatic system would be unable to function without a central pump.

Explanation:

The molecule that carries a great deal of chemical energy in its chemical bonds and is made in both photosynthesis and cellular respiration is
DNA
RNA
NADPH
ATP
Glucose

Answers

The answer is glucose

Which is true of the amount of matter in ecosystems?
a). It decreases over time.
b). It remains constant.
c). Scientists cannot determine how it changes.
d). It increases over time.

Answers

Answer:

I think its c Scientists cannot determine how it changes.

d). It increases over time.

The true fact about the amount of matter in ecosystems is that it remains constant, as shown in Option b, the amount of matter in an ecosystem remains constant according to the law of conservation of matter.

What is the significance of ecosystems?

An ecosystem is an interaction between living organisms and their environment, and the interactions between them are important because they provide a wide range of benefits to humans, including supporting livelihoods, providing food, purifying the air and water, regulating the climate, and also playing a vital role in maintaining the balance of nature and providing a home for a diverse range of species.

Hence, the true fact about the amount of matter in ecosystems is that it remains constant, as shown in Option b, the amount of matter in an ecosystem remains constant according to the law of conservation of matter.

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El numero de doploide de cromosomas de la especie humana que se restablece durante la

Answers

Answer:

El numero diploide de la especie humana se restablece durante la fecundación del ovulo por parte del espermatozoide, en donde estas dos células haploides (23 cromosomas) se unen formando un cigoto y próximamente un feto que poseerá los 46 cromosomas necesarios para la formación de un ser humano

Explanation:

Do plants produce more oxygen than they need?​

Answers

Answer:

Photosynthesis uses carbon dioxide to make sugar and produces oxygen as a byproduct. Respiration uses oxygen to release energy from stored sugar and produces carbon dioxide as a byproduct. ... However, if the plants are growing, then over a period of 24 hours they will produce more oxygen than they consume.

She is right because I did that to

Use evidence from the Grants’ research to explain how natural selection leads to evolution. (10 points)

Answers

Answer:

The correct answer is - Grant's research on finches on the Galapagos islands.

Explanation:

Grant's research was made on medium-sized finches on the Galapagos islands showed evolutionary processes in real-time. He showed that due to the drought there is a decrease in the number of small and soft seeds that were finches major food source.

It is known that there are different beak sizes in this finch species, the finches with larger beaks could feed on tough and large seeds and survive in such case of the drought-induced decrease in food availability. Due to this natural selection and adaption the number of larger beaks in finches is increased over the real time.

Answer:

Grant's research on finches on the Galapagos islands.

Explanation:

An easy 10 points
Make up your own scientific theory.

Answers

Answer:

Ammmmm theory focused on the structuralist or central-peripheral paradigm, the analysis of internal colonialism and marginality, and studies on dependence are discussed here. Wherever they come, the divergent key positions of the Latin American school are important.

When people work with volatile organic
compounds, why should they wear special masks
that cover their noses and mouths

Answers

Answer:

harmful to the lungs........................

Write a complete sentence for the word Germinal period

Please help !!!

Answers

48394593828393933837282929

Answer:

The germinal period (about 14 days in length) lasts from conception to implantation of the zygote (fertilized egg) in the lining of the uterus.

Why are all X-linked alleles expressed in males, even if they are recessive?

Answers

Answer:

It is because Males have just one X chromosome. X-linked recessive alleles are expressed in males because males have only one X-chromosome.

Have a nice day!

and can I maybe have brainliest? Thanks!

Pls help - will give brainliest

Answers

Answer:

Claim- A direct response that answers the question or problem

Evidence- The actual lab data or reliable source/text that supports the claim

Reasoning- Explains how and why the evidence supports the claim, providing a logical connection between the evidence and claim

Explanation:

The claim is the start of your essay that addresses the topic. The evidence should be factual and concise and the reasoning supports your evidence

which technique is used for the separation of leaf pigments​

Answers

Answer:

hope this helps you byee

Water loss in plants is usually a result of transpiration. Which of the following best describes the path that water will follow from the root system to the shoot system utilizing the vascualr system?


A. to increase tolerance of environmental extremes
B. to accelerate the process of natural selection
C. to maintain homeostasis
D. to adapt to their environment

Answers

c to maintain homeostasis

It is c because it wants to regulate the amount of water in it's system

What does it mean for an enzyme to denature? *
A. Enzyme is activated
B. Enzyme is split
C. Enzyme permanently changed shape
D. Enzyme is catalyzing

Answers

Answer: Higher temperatures disrupt the shape of the active site, which will reduce its activity, or prevent it from working. The enzyme will have been denatured . ... The enzyme, including its active site, will change shape and the substrate no longer fit. The rate of reaction will be affected, or the reaction will stop. So the answer is c i hope this helped:)

Explanation:

I believe it’s C: enzyme permanently changed shape

Which of the following is true about genes?
A.
In humans, genes are passed to an offspring from two parents.
B.
The genes of a particular organism can never change throughout its lifetime.
C.
Genes are made up of smaller molecules known as chromosomes.
D.
Genes are responsible for all the traits of an organism.

Answers

Answer:

i think its A

Explanation:

Main features of Solar System, Main facts of solar system

Answers

Answer:

The main features of the solar system:

The Sun is our nearest star.

The planets orbit the Sun.

The time taken to orbit the Sun increases with distance from the Sun.

Gravity keeps the planets in orbit around the Sun and the moons in orbit around their planets.

From the Sun, the order of the planets is Mercury, Venus, Earth, Mars, Jupiter, Saturn, Uranus, and Neptune. You might need to be able to recall this in the exam.

The planets go around the Sun in slightly squashed circular elliptical orbits.

Pluto is classified as a dwarf planet or planetoid. It has a highly elliptical or eccentric orbit.

Main facts

The definition of a planet and a moon is fuzzy. ...

Comets and asteroids are leftovers. ...

The planets are all on the same “plane” and orbit in the same direction. ...

We're nowhere near the center of the galaxy. ...

But the Solar System is bigger than you think. ...

The Sun is hugely massive. ...

Explanation: (:

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